To meet the demand of flexible and practical talents under the background of the construction of the Hainan Free Trade Port, we take the comprehensive communication ability as an example to discuss the development path of three abilities needed by English majors – general communication ability, professional application abilities, and cross-cultural communication —and analyses the current issues of college English teaching, such as one-size-fits-all objectives setting, mismatching of course contents with industrial requirements, and single and inflexible pedagogical approach. Based on the idea of industry relevance, competency-oriented education, and diversity of combination modes, the paper presents new ideas in three aspects: adjustment of hierarchical and classified educational goals, constructing a flexible module-based course framework based on the actual situation of the Free Trade Port, and building up an “school-enterprise cooperation + internet empowerment” education mode. It analyzes a three-in-one cultivation pattern integrating English communication ability, Free Trade Port-related industry knowledge, and Intercultural ability, providing concepts and direction to cultivate English talents in the background of the Free Trade Port.