ARTICLE
25 August 2023

A Single Nonsteroidal Anti-Inflammatory Drugs-Induced Anaphylaxis to Diclofenac Confirmed by Skin Testing

Hana Lee1,2,3 Jung-Hyun Kim3 Yong-Hyun Kim1,2 Bomi Seo4 Sae-Hoon Kim1,2,5 Yoon-Seok Chang1,2,5
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1 Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
2 Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea
3 Department of Internal Medicine, The Armed Forces Capital Hospital, Seongnam, Korea
4 Department of Internal Medicine, Seongnam Citizens Medical Center, Seongman, Korea
5 Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Council, Seoul, Korea
JMDS 2023 , 8(1), 18–24; https://doi.org/10.18063/jmds.v8i1.145
© 2023 by the Authors. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution -Noncommercial 4.0 International License (CC BY-NC 4.0) ( https://creativecommons.org/licenses/by-nc/4.0/ )
Abstract

Anaphylaxis is a serious acute systemic allergic reaction that can lead to death, thus requiring immediate diagnosis and treatment. In particular, food is the most common cause of anaphylaxis in children, adolescents, and young adults. In addition to physical contact with food, anaphylaxis can also be induced by exposures other than ingestion, such as the inhalation of aerosolized food proteins. Korean males undergo medical screening prior to a compulsory military service. A history of possible food allergy requires referral to a specialized allergy clinic. It was reported in 2021 that a 19-year-old male patient enlisted in the military was referred to the allergy clinic for an oral provocation test. That case confirmed that anaphylaxis was caused not only by walnut intake, but also by skin contact or by inhaling walnut particles, which will be reviewed in this paper.

References

Jang GC, Chang YS, Choi SH, et al., 2013, Overview of Anaphylaxis in Korea: Diagnosis and Management. Allergy

Asthma Respir Dis, 1: 96–181.

Johnson RM, Barnes CS, 2013, Airborne Concentrations of Peanut Protein. Allergy Asthma Proc 34: 59–64.

Yu JE, Lin RY, 2018, The Epidemiology of Anaphylaxis. Clin Rev Allergy Immunol, 54: 366–374.

Yang MS, Lee SH, Kim TW, et al., 2008, Epidemiologic and Clinical Features of Anaphylaxis in Korea. Ann Allergy

Asthma Immunol, 100: 31–36.

Lieberman P, Nicklas RA, Randolph C, et al., 2015, Anaphylaxis — A Practice Parameter Update. Ann Allergy

Asthma Immunol, 115: 341–384.

Lee SC, Kim SR, Park KH, et al., 2019, Clinical Features and Culprit Food Allergens of Korean Adult Food Allergy

Patients: A Cross-Sectional Single-Institute Study. Allergy Asthma Immunol Res, 11: 723–735.

Roberts G, Golder N, Lack G, 2002, Bronchial Challenges with Aerosolized Food in Asthmatic, Food-Allergic

Children. Allergy, 57: 713–717.

Lee YH, 2019, Korean Air, which also Pulled Out ‘Peanut’, “Priority to Passenger Health,” Korea Economics TV,

viewed Jun 15, 2020, http://www.wowtv.co.kr/NewsCenter/News/Read?articleId=A201903310036&t=NN

Kim SH, 2018, Singapore Airlines Suspends On-Board Peanut Service Because of Allergies Yonhap News, viewed Jun 17, 2020, http://yna.co.kr/view/AKR20180430165200076?input=1195m

Byeong-yeogbeob [Military Service Act], art. 5, amended by Act No. 17166, March 31, 2020, viewed, 2020 Jun 10,

http://www.law.go.kr/ 법령 / 병역법

Byeong-yeogpanjeong sinchegeomsa deung geomsagyuchig (yagching: byeong-yeogsinchegeomsagyuchig)

[Examination rules for military examination physical examination (abbreviation: Military Examination Rules)], art.

, Sep 17, 2018, viewed, Jun 15, 2020, http://www.law.go.kr/ 법령 / 병역판정신체검사등검사규칙

Lieberman P, Nicklas RA, Randolph C, et al., 2015, Anaphylaxis — A Practice Parameter Update, Ann Allergy

Asthma Immunol 2015;115:341-84.

Mehta H, Groetch M, Wang J, 2013, Growth and Nutritional Concerns in Children with Food Allergy. Curr Opin

Allergy Clin Immunol, 13: 275–279.

Feuille E, Nowak-Wegrzyn A, 2018, Allergen-Specific Immunotherapies for Food Allergy. Allergy Asthma Immunol

Res, 10: 189–206.

Kim MH, Suh DI, Lee SY, et al., 2016, Microbiome Research in Food Allergy and Atopic Dermatitis. Allergy Asthma

Respir Dis, 4: 389–398.

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