Volume 10,Issue 4
Risk Factors and Prognostic Analysis of Postoperative Entrapped Temporal Horn (ETH) Following Tumor Resection in the Trigone of the Lateral Ventricle
Objective: This study aims to investigate the independent risk factors for postoperative entrapped temporal horn (ETH) following surgery for trigone zone tumors of the lateral ventricle and its impact on patients' short-term and long-term outcomes, thereby providing scientific evidence for early clinical diagnosis and intervention. Methods: A multicenter retrospective analysis was conducted on 68 patients who underwent surgery for trigone zone tumors of the lateral ventricle between January 2011 and December 2021 and met the inclusion and exclusion criteria. Pre- and postoperative clinical and imaging data were collected. Univariate and multivariate logistic regression analyses were performed to assess the association between surgical factors and the occurrence of ETH, and the impact of ETH on patients' neurological outcomes was evaluated. Results: The incidence of ETH in this study was 18.5%. Multivariate logistic regression analysis showed that tumor diameter ≥3.2 cm (P=0.001), tumor location in the trigone (P=0.021), postoperative meningitis (P=0.006), and tumor hemorrhage (P=0.002) were independent risk factors for ETH. Radiologically, ETH patients exhibited isolated temporal horn dilation shortly after surgery, with significantly more severe neurological deficits (such as contralateral homonymous hemianopia, memory and emotional disorders) and a significantly higher rate of reoperation. Additionally, patients who did not receive external ventricular drainage postoperatively had a higher risk of developing ETH (P=0.012). Conclusion: The occurrence of ETH is closely associated with tumor location, size, surgical procedure, and postoperative complications, significantly affecting patients' postoperative neurological outcomes. Clinically, screening high-risk patients, enhancing perioperative monitoring of the ventricular system, and improving postoperative inflammation management are crucial steps that may help reduce ETH incidence and improve outcomes. Future studies should focus on multicenter prospective cohort studies and long-term follow-up to further validate risk factors and evaluate the effectiveness of various interventions.
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