REVIEW ARTICLE

Volume 10,Issue 4

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12 June 2015

Philanthropies as partners for drug development in  public–private partnerships

Mark D. Lim1 Martha A. Brumfield2 Michel Goldman3*
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1 FasterCures, a Center of the Milken Institute, Washington, DC 20005, USA
2 Critical Path Institute, Tucson, AZ 85718, USA
3 Institute for Interdisciplinary Innovation in Healthcare, Université Libre de Bruxelles, 1070 Brussels, Belgium
JMDS 2016 , 1(1), 10–13; https://doi.org/10.18063/jmds.v1i1.107
Submitted: 13 May 2015 | Accepted: 30 May 2015
© 2016 by the Author(s). Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution -Noncommercial 4.0 International License (CC BY-NC 4.0) ( https://creativecommons.org/licenses/by-nc/4.0/ )
Abstract

Disease-focused philanthropic organizations play an increasing role in the strategy and conduct of biomedical  research, with many focusing on drug development for specific diseases and patient populations. More and more they  not only provide resources and expertise, but also take active part managing the strategy and objectives of targeted research programs, using approaches such as venture philanthropy. Many also lead and participate in public–private partnerships. One example is the partnership between the Polycystic Kidney Disease (PKD) Foundation and the Critical  Path Institute (C-Path) which brings together several pharmaceutical companies and academic institutions to develop  new broadly-used biomarkers. Another case is the partnership between JDRF (formerly known as the Juvenile Diabetes  Research Foundation) and the Innovative Medicines Initiative (IMI), involving financial support of the IMIDIA project  (Innovative Medicines Initiative for Diabetes) which is focused on improving beta-cell function and identifying biomarkers for diabetes treatment monitoring. These examples show that in addition to providing financial support and  expertise, philanthropic foundations are also in a unique position to coordinate the patient and research communities to  enable and accelerate specific medicines development projects.

Keywords
Philanthropic foundation
venture philanthropy
polycystic kidney disease
type 1 diabetes
References

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Conflict of interest
Martha Brumfield is the President and CEO of the Critical Path Institute; Michel Goldman is the former executive director of the Innovative Medicines Initiative.
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