With the rapid development of society, college students are increasingly burdened by psychological pressures such as academic stress and employment challenges. Effectively alleviating these pressures and promoting mental health has become a key focus in contemporary educational research. As a unique art form, piano art possesses rich emotional expression and psychological regulation capabilities. This study explores the application of piano art in psychological adjustment and stress relief for college students, analyzing its role in reducing psychological stress, enhancing emotional regulation, and improving mental resilience. Through literature review and case studies, the paper proposes that piano art serves as an effective intervention for psychological adjustment and stress relief among college students, demonstrating promising application prospects.