Objective: To explore the application value of flexible management concepts in the nursing management process of psychiatric hospitals. Methods: This article selects inpatients in a psychiatric hospital as the research object. The inclusion time is between February 2024 and October 2025. According to statistics, a total of 60 patients are included in the above patients. They are divided into 2 groups according to the order of admission time, including: control group (admitted from February 2024 to December 2024, n = 30 cases), experimental group (admitted from January 2025 to October 2025, n = 30 cases); during the clinical treatment stage, routine nursing management was provided to the control group, and nursing intervention under the flexible management concept was provided to the experimental group. The final effects were compared, including: the quality of staff nursing management, the incidence of adverse events, and the satisfaction of inpatients. Results: (1) The quality of nursing management of psychiatric hospital staff was analyzed. In terms of basic care, safety management, nursing documentation, and patient education, the experimental group scored higher than the control group, P < 0.05; (2) In the incidence of adverse events among inpatients, the ratio was 26.67% in the experimental group and 6.67% in the control group. The comparison results showed that the experimental group was lower, P < 0.05; (3) Nursing management satisfaction comparison, (76.67%) VS (96.67%), the experimental group was higher among inpatients, P < 0.05. Conclusion: Nursing intervention under the concept of flexible management is clinically important. For inpatients in psychiatric hospitals, it can reduce the incidence of adverse events and improve satisfaction. At the same time, the implementation of the above program can also improve the work quality of nursing staff and has significant promotional value.