The emerging economic landscape has placed increasing emphasis on cultivating interdisciplinary innovative talents, with higher education institutions serving as crucial platforms for talent development that must proactively address industrial transformation demands. This study examines innovation and entrepreneurship competencies as a focal point, conducting an in-depth analysis of their structural framework and implications. It elucidates novel requirements for practical teaching methodologies while systematically identifying key challenges in current business administration practice education. Building upon this foundation, the paper proposes concrete reform strategies including: redefining practice-oriented objectives, implementing dynamic case-based teaching approaches, integrating real-world business projects, establishing cross-disciplinary collaboration platforms, and developing formative assessment systems. These initiatives aim to provide actionable pathways for nurturing versatile management professionals with value-creation capabilities.