Under the framework of vocational undergraduate education, the applied chemical technology program aims to cultivate high-level technical professionals, with engineering practice capabilities occupying a central position in the talent development system. However, practical teaching processes still face challenges, including insufficient integration between theoretical instruction and engineering practice, mismatched practical content with job requirements, and inadequate evaluation systems for practical competencies. Addressing these issues, this study proposes teaching reform strategies and implementation pathways through curriculum goal restructuring, content optimization, theory-practice integration with project-based teaching, enhanced practical teaching facilities, and improved evaluation mechanisms. The research demonstrates that practice-oriented teaching reforms can effectively enhance students’ operational skills and engineering problem-solving abilities, holding significant practical value for improving the quality of applied chemical technology talent cultivation.